Guodong Liang | Medicinal | Young Scientist Award

Assoc Prof Dr. Guodong Liang | Medicinal | Young Scientist Award

Senior Engineer at Inner Mongolia Medical University, China

Summary:

Assoc Prof Dr Guodong Liang is a senior engineer and master tutor at the College of Pharmacy, Inner Mongolia Medical University. Specializing in peptide-based antiviral research, Dr. Liang completed his Bachelor’s and Master’s degrees at Shenyang Pharmaceutical University in 2012 and 2015, respectively, and earned his Ph.D. from the Beijing Institute of Pharmacology and Toxicology in 2018. His research focuses on innovative peptide fusion inhibitors for treating viral infections, including HIV-1 and SARS-CoV-2. Notable for his contributions to peptide science, Dr. Liang has published extensively, holds a U.S. patent, and has received funding from various prestigious programs.

 

Profile:

Education:

Assoc Prof Dr Guodong Liang earned his Bachelor’s degree in Pharmacy from Shenyang Pharmaceutical University in 2012. He continued his studies at the same institution, obtaining a Master’s degree in Pharmaceutical Sciences in 2015. Further advancing his academic career, he completed his Ph.D. in Pharmacology and Toxicology at the Beijing Institute of Pharmacology and Toxicology in 2018. His educational background has provided a strong foundation for his research in peptide-based antiviral strategies.

Professional Experience:

Assoc Prof Dr Guodong Liang is a senior engineer and master tutor at the College of Pharmacy, Inner Mongolia Medical University. In this role, he leads research and teaching initiatives, focusing on peptide-based antiviral therapies. Prior to his current position, Dr. Liang has accumulated extensive experience in peptide research and development. His expertise encompasses the design of peptide fusion inhibitors and contributions to significant research projects funded by various programs, including the Inner Mongolia Natural Science Foundation and Inner Mongolia Medical University. His professional background reflects a commitment to advancing antiviral research and educating the next generation of scientists.

Research Interests:

Assoc Prof Dr Guodong Liang’s research interests are centered around peptide-based antiviral therapies. His work primarily focuses on the development and application of peptide fusion inhibitors to combat viral infections. Notable areas of his research include the design of isopeptide bond bundling superhelixes and their application in creating inhibitors against viruses such as HIV-1 and SARS-CoV-2. Dr. Liang explores innovative methods for developing broad-spectrum antiviral peptide drugs, aiming to enhance the efficacy of treatments for various viral diseases. His research integrates advanced peptide chemistry with practical antiviral applications, contributing to the field of pharmaceutical science.

Skills:

Assoc Prof Dr Guodong Liang possesses a robust skill set in peptide chemistry and antiviral drug development. His expertise includes designing and synthesizing peptide-based fusion inhibitors, with a focus on creating isopeptide bond bundling superhelixes for antiviral applications. Dr. Liang is proficient in advanced techniques for peptide analysis and evaluation, including structural and functional assessments of peptide interactions with viral proteins. His skills extend to securing and managing research funding, conducting collaborative projects, and publishing high-impact scientific papers. With a strong foundation in pharmacology and toxicology, Dr. Liang effectively translates complex scientific concepts into practical antiviral solutions.

Conclution:

Dr. Liang’s pioneering work in peptide-based antiviral research, evidenced by his impactful publications, patents, and innovative projects, demonstrates his significant contributions to the field. His research not only advances the design of targeted antiviral therapies but also lays the groundwork for developing broad-spectrum antiviral drugs, marking him as a leading candidate for the Research for Young Scientist Award.

Publication Tob Noted:

A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity

  • Authors: Li, Y.-Y., Liang, G.-D., Chen, Z.-X., Liu, S.-W., Yang, J.
  • Journal: Acta Pharmacologica Sinica, 2024

Isopeptide Bond Bundling Superhelix for Designing Antivirals against Enveloped Viruses with Class I Fusion Proteins: A Review

  • Authors: Na, H., Liang, G., Lai, W.
  • Journal: Current Pharmaceutical Biotechnology, 2023, 24(14), pp. 1774–1783

Hipponorterpenes A and B, two new 14-noreudesmane-type sesquiterpenoids from the juice of Hippophae rhamnoides

  • Authors: Zhang, X.-L., Na, H.-Y., Li, P.-S., Liang, G.-D., Hua, H.-M.
  • Journal: Phytochemistry Letters, 2022, 52, pp. 82–86

De Novo Design of α-Helical Lipopeptides Targeting Viral Fusion Proteins: A Promising Strategy for Relatively Broad-Spectrum Antiviral Drug Discovery

  • Authors: Wang, C., Zhao, L., Xia, S., Jiang, S., Liu, K.
  • Journal: Journal of Medicinal Chemistry, 2018, 61(19), pp. 8734–8745

 

Wolnei Caumo | Medical award | Best Researcher Award

Prof Dr. Wolnei Caumo, Medical Award, Best Researcher Award

Professor at UFRGS, Brazil

Prof. Dr. Wolnei Caumo is a distinguished expert in the fields of anesthesia, pain management, and clinical research. As the Director of the Pain & Neuromodulation Laboratory at Hospital de Clínicas de Porto Alegre (HCPA) and Full Professor of Anesthesia and Pain at the Medical School of Universidade Federal do Rio Grande do Sul (UFRGS) in Porto Alegre, Brazil, he has made significant contributions to advancing the understanding and treatment of chronic pain conditions. Dr. Caumo’s research focuses on neurophysiological markers of pain processing, biomarkers of neuroplasticity in chronic pain, and therapeutic interventions such as pharmacological and non-invasive brain stimulation techniques. He is renowned for his dedication to education and mentorship, guiding numerous students and research fellows in pain management practices. Dr. Caumo’s work has earned him widespread recognition and respect, and he continues to lead innovative research efforts aimed at improving the lives of individuals living with chronic pain.

Profile:

Education:

  • M.D. from Universidade Federal de Pelotas, Brazil (1992)
  • Residency in Anesthesia at Hospital de Clínicas de Porto Alegre, Brazil (1994)
  • M.Sc. in Medicine from Universidade Federal do Rio Grande do Sul, Brazil (1997)
  • Specialist in Pain and Palliative Medicine from Universidade Federal do Rio Grande do Sul, Brazil (2000)
  • Ph.D. in Medicine with specialization in Pain from Universidade Federal do Rio Grande do Sul, Brazil (2001)
  • Clinical Research Course from Harvard Medical School, USA (2011)

Professional Experience:

Prof. Dr. Wolnei Caumo holds several prominent positions in the field of anesthesia, pain management, and research. He is currently serving as a Full Professor of Anesthesia and Pain at the Medical School of Universidade Federal do Rio Grande do Sul in Porto Alegre, Brazil, a position he has held since 2003. Additionally, he serves as the Head of Service in Pain and Palliative Care at Hospital de Clínicas de Porto Alegre, where he has been contributing since 2017. Dr. Caumo is also the Director of the Laboratory of Pain & Neuromodulation at the same hospital, a role he has held since 2009. Over the years, he has been actively involved in coordinating various academic programs, including the Specialized Medical Care for Pain and Palliative Medicine Course and the Graduate Program in Medical Sciences at Universidade Federal do Rio Grande do Sul. Furthermore, he has been a Coordinator of the Center and teacher assistance of the Course in Principles and Practice of Clinical Research at Harvard Medical School since 2012. Dr. Caumo’s dedication to education and research in pain management has made him a respected figure in the field, both nationally and internationally.

Research Interest:

Prof. Dr. Wolnei Caumo’s research interests primarily revolve around pain management and neuromodulation approaches. He is particularly focused on investigating the neurophysiological mechanisms underlying chronic pain processing, including central sensitization and cortical excitability. Dr. Caumo’s research aims to identify biomarkers of neuroplasticity in musculoskeletal chronic pain conditions and explore therapeutic interventions to counteract maladaptive neuroplasticity. Additionally, he is interested in the therapeutic potential of non-invasive brain stimulation techniques, such as transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS), in modulating pain perception and improving clinical outcomes in patients with chronic pain syndromes. His work also encompasses the evaluation of pharmacological interventions and the development of personalized treatment approaches based on individual neurobiological profiles. Overall, Prof. Dr. Wolnei Caumo’s research endeavors contribute to advancing our understanding of pain mechanisms and developing innovative strategies for pain management.

Publication Top Noted:

“Cross-sectional and longitudinal analysis of conditioned pain modulation and pain in fibromyalgia: CPM as an effect modifier of pain changes over time”:

  • Authors: Castelo-Branco, L., Pacheco-Barrios, K., Cardenas-Rojas, A., Caumo, W., Fregni, F.
  • Journal: Physiotherapy Research International
  • Year: 2024
  • Volume: 29
  • Issue: 2
  • Pages: e2072

“Impact of multiple-session home-based transcranial direct current stimulation (M-HB-tDCS) on eating behavior in fibromyalgia: A factorial randomized clinical trial”:

  • Authors: Jornada, M.N.D., Antunes, L.C., Alves, C., P Silva, D., Caumo, W.
  • Journal: Brain Stimulation
  • Year: 2024
  • Volume: 17
  • Issue: 2
  • Pages: 152–162

“Efficacy of Home-Based Transcranial Direct Current Stimulation Over the Primary Motor Cortex and Dorsolateral Prefrontal Cortex in the Disability Due to Pain in Fibromyalgia: A Factorial Sham-Randomized Clinical Study”:

  • Authors: Caumo, W., Lopes Ramos, R., Vicuña Serrano, P., LS Torres, I., Fregni, F.
  • Journal: Journal of Pain
  • Year: 2024
  • Volume: 25
  • Issue: 2
  • Pages: 376–392

“Troponin elevation as a marker of short deterioration and one-year death in a high-risk surgical patient cohort in a low and middle-income country setting: a postoperative approach to increase surveillance”:

  • Authors: Stahlschmidt, A., Passos, S.C., Dornelles, D.D., Caumo, W., Ferreira, M.
  • Journal: Canadian Journal of Anesthesia
  • Year: 2023
  • Volume: 70
  • Issue: 11
  • Pages: 1776–1788

Transcranial Direct Current Stimulation (tDCS) Promotes state-dependent Effects on Neuroinflammatory and Behavioral Parameters in rats Chronically Exposed to Stress and a Hyper-Palatable Diet”:

  • Authors: de Castro, J.M., de Freitas, J.S., Stein, D.J., Caumo, W., Torres, I.L.S.
  • Journal: Neurochemical Research
  • Year: 2023
  • Volume: 48
  • Issue: 10
  • Pages: 3042–3054

“Preemptive transcranial direct current stimulation induces analgesia, prevents chronic inflammation and fibrosis, and promotes tissue repair in a rat model of postoperative pain”:

  • Authors: Zancanaro, M., Stein, D.J., Lopes, B.C., Caumo, W., Torres, I.L.S.
  • Journal: Neuroscience Letters
  • Year: 2023
  • Volume: 813
  • Pages: 137407